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Direct potable reuse of wastewater is attractive as the demand for potable water increases. However, the presence of organic micropollutants in industrial and domestic wastewater is a major health and environmental concern. Conventional wastewater treatment processes are not designed to remove these compounds. Further many of these emerging pollutants are not regulated. Membrane bioreactor based biological wastewater treatment has recently become a preferred method for treating municipal and other industrial wastewaters. Here the removal of five selected micropollutants representing different classes of emerging micropollutants has been investigated using a membrane bioreactor. Acetaminophen, amoxicillin, atrazine, estrone, and triclosan were spiked into wastewaters obtained from a local wastewater treatment facility prior to introduction to the membrane bioreactor containing both anoxic and aerobic tanks. Removal of these compounds by adsorption and biological degradation was determined for both the anoxic and aerobic processes. The removal as a function of operating time was investigated. The results obtained here suggest that removal may be related to the chemical structure of the micropollutants.